Biotechnology of Genes and Proteins
Duration
- One Semester or equivalent
Contact hours
- 60
On-campus unit delivery combines face-to-face and digital learning.
2022 teaching periods
| Hawthorn Higher Ed. Semester 2 |
||
|---|---|---|
Dates: Results: Last self enrolment: Census: Last withdraw without fail: |
Aims and objectives
The unit aims to provide the students with the fundamentals of prokaryotic gene structure and regulation, an overview of the complexity, organisation and instability of the eukaryotic genomes, the structure, functions and mechanisms of regulation of eukaryotic genes, the genetic basis of various human diseases, the biochemical properties and functions of select proteins, an understanding of the applications of gene and protein analyses in diverse fields of modern biological and molecular sciences, and laboratory exercises that provide a greater understanding of these areas.
Unit Learning Outcomes
Students who successfully complete this unit will be able to:
1. Demonstrate an understanding of the structures and functions of diverse types of proteins
2. Demonstrate an understanding of the complexity of eukaryotic genes and genomes and the significance of these
3. Explain the complexities of regulation of gene expression, especially in eukaryotes, their significance and applications, including an appreciation of new discoveries and technologies
4. Show an understanding of the diverse molecular technologies used for analysis of genes and/or proteins, including applications of computer-based technologies
5. Describe the nature and major mechanisms of genetic variability, recombinations and/or instability in the human and other genomes, and the significance of these
6. Demonstrate advanced laboratory skills where the theoretical knowledge in a selection of the above areas is applied to practical situations, and record the scientific observations correctly, analyse and interpret the results critically, and report professionally
Unit Learning Outcomes
Students who successfully complete this unit will be able to:
1. Demonstrate an understanding of the structures and functions of diverse types of proteins
2. Demonstrate an understanding of the complexity of eukaryotic genes and genomes and the significance of these
3. Explain the complexities of regulation of gene expression, especially in eukaryotes, their significance and applications, including an appreciation of new discoveries and technologies
4. Show an understanding of the diverse molecular technologies used for analysis of genes and/or proteins, including applications of computer-based technologies
5. Describe the nature and major mechanisms of genetic variability, recombinations and/or instability in the human and other genomes, and the significance of these
6. Demonstrate advanced laboratory skills where the theoretical knowledge in a selection of the above areas is applied to practical situations, and record the scientific observations correctly, analyse and interpret the results critically, and report professionally
Unit information in detail
- Teaching methods, assessment, general skills outcomes and content.
Teaching methods
*Scheduled face to face: Lectures (36 hours), Laboratory Work (24 hours)
*Scheduled synchronous online learning events (N/A)
Non-scheduled online learning events and activities (10-12 hours)
Other non-scheduled learning events and activities including independent study (approx. 80 hours)
*Scheduled synchronous online learning events (N/A)
Non-scheduled online learning events and activities (10-12 hours)
Other non-scheduled learning events and activities including independent study (approx. 80 hours)
Assessment
| Types | Individual or Group task | Weighting | Assesses attainment of these ULOs |
| Practical work | Individual | 25-35% | 1,2,4,5,6 |
| On-line quizzes | Individual | 5-10% | 1,2,3,4,5 |
| Test(s) | Individual | 20-25% | 1,2,3,4,5 |
| Final exam | Individual | 35-40% | 1,2,3,4,5 |
Minimum requirements to pass this unit
As the minimum requirements of assessment to pass the unit and meet all Unit Learning Outcomes to a minimum standard, a student must achieve:
(i) An aggregate mark of 50% or more, and
(ii) Obtain at least 40% in the final exam, and
(iii) Complete a minimum of 80% of laboratory work based on the criteria for successful completion as explained in the lab handout(s).
Students who do not successfully achieve hurdle requirements (ii) and (iii) will receive a maximum of 44% as the total mark for the unit and will not be eligible for a conceded pass.
General skills outcomes
You will be provided with feedback on your progress in attaining the following generic skills:
• teamwork skills
• analysis skills,
• problem solving skills
• communications skills,
• ability to tackle unfamiliar problems,
• ability to work independently
• teamwork skills
• analysis skills,
• problem solving skills
• communications skills,
• ability to tackle unfamiliar problems,
• ability to work independently
Content
• Structure and functions of diverse types of proteins
• Structure and functions of DNA and other nucleic acids
• Principles of DNA replication
• Gene structure and regulation in bacteria, the lac operon and its applications
• Composition of eukaryotic genomes, including the human genome
• Eukaryotic gene structures and mechanisms of regulation of gene expression
• Repetitive DNA sequences, their structures, functions, variability, instability, applications
• Mechanisms of different types of genetic recombinations, their significance
• Genetic instability, mobile genetic elements
• Molecular basis of selected human genetic diseases
• Laboratory and/or computer work to apply selected biochemical and molecular techniques for analyses of nucleic acids and proteins
• Structure and functions of DNA and other nucleic acids
• Principles of DNA replication
• Gene structure and regulation in bacteria, the lac operon and its applications
• Composition of eukaryotic genomes, including the human genome
• Eukaryotic gene structures and mechanisms of regulation of gene expression
• Repetitive DNA sequences, their structures, functions, variability, instability, applications
• Mechanisms of different types of genetic recombinations, their significance
• Genetic instability, mobile genetic elements
• Molecular basis of selected human genetic diseases
• Laboratory and/or computer work to apply selected biochemical and molecular techniques for analyses of nucleic acids and proteins
Study resources
- References.
References
A list of reading materials and/or required texts will be made available in the Unit Outline.