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Bio Technology


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Biomolecular and Cellular Microengineering

Research Activities

The Biomolecular and Cellular Microengineering Group focuses on the understanding, prediction and design of processes that depend upon the interaction of biological objects (biomolecules and/or cells) with micro- and nano-structured surfaces.

Research falls into the following categories:

  • Control of protein molecular motor motion in manufactured electro-mechanical devices
  • Micro/nano-profiled and electrically-active surfaces to probe the response of biomolecules for micro/nano-array applications
  • Effective, non-denaturating technologies for immobilization of biomolecules in static (e.g. biosensors) and dynamic (e.g. microfluidics) biodevices
  • Probing of microorganism responses to micro-structured and micro-confined environments

Laboratory Facilities

Includes 3 clean rooms, housing a range of specialised equipment.

  1. Biofunctional Imaging Lab
    • Olympus FV1000 confocal microscope
    • Cell Robotics laser scissors/tweezers workstation
    • Low light/dynamic cellular/fluorescence microscopy workstation (Olympus IX71, Photonics Science CoolView FDI CCD camera, Image Pro software).
  2. Surface Fabrication and Characterisation Lab
    • Dip Pen Nanolithogrophy Instrumentation (NSCRIPTOR™ DPNWriter)
    • Thermomicroscopes Atomic Force Microscope
    • Spin coater
    • FTIR spectrometer
    • Quartz Crystal Microbalance
    • Ellipsometer
    • Contact Angle Goniometer
  3. Wet Lab
    • Used for biomolecular and microbiological preparation and characterisation

Tissue Engineering

Research Leader

Biomedical and Electronic Microwave Systems & Technology

Research Leader

Typical Publication and Patents

  1. MM Wave radiometers complex. Conference Digest. 16th International on IR and MM Waves. Lausanne, Switzerland, 1991, 626-627.
  2. Devices for Microwave Resonance Therapy. Proc. of Fifth Australian Symposium on Millimetre And Submillimetre Waves. Adelaide, Australia. 1992.
  3. High Power IMPATT Noise Sources for the Active-Passive RADAR. Proc. of Fifth Australian Symposium on Millimetre and Submillimetre Waves. Adelaide, Australia. 1992. pp. 96-97
  4. Principles of Applied Biomedical Microwave Instrumentation. Proc. of 23 European Microwave Conference. Madrid, Spain. 1993.
  5. Low-level Millimetre Bioelectromagnetic Instrumentation. Proc. of 4th International Symposium on Recent Advance in microwaves Technology. New Delhi, Agfa, India. 1993.
  6. Devices for Microwave Resonance Therapy. Proc. of 23 EuMC -93, Madrid, Spain, Sept. 6-9, 1993, 52-57.
  7. Devices for Biomedical Non-Thermal Millimetre Wave Radiation. Proc. of 1994 Asia-Pacific Microwave Conference - ARMC’ 94. Tokyo, Japan. 1994.
  8. Devices for Microwave Power Engineering. Proc. of Microwave’ 94, New Zealand’s First Microwave Symposium, Auckland, NZ. 1994.
  9. IMPATT Oscillators with Varactor Tuning for Short Millimetre-Wave Band. Proc. of ICEMI’ 95. International Conference on Electronic Measurement. Shanghai, China
  10. Frequency Filtering in the Short MM Wave Bands. International J. of IR and MM Waves, vol 16, N 2, 1995, 78-83.
  11. Extremely High Frequency (EHF) Therapy. Complementary Medicine International, 1996, 3 (1): 29.35.
  12. Tunable Oscillator and it's Tuning Method. USSR Patent No. 4768590/09/ 89.
  13. Millimetre wave VCO. USSR Patent No. 3990567/95
  14. Method of non-contact influence on objects' zone and points of minimum resistance and device for its implementation. Republic of Armenia Patent No GP-987.
  15. Microwave Resonance Therapy device. USSR Patent 4739197/14.1997
  16. Microwave Hot Water System. Petty patent.1998

Typical Research Projects

  • Microwave Arcjet Thruster
    Objective:
    To design microwave acrjet thruster ruses microwave energy to create a free-floating plasma discharge within microwave resonance cavity.
  • Microwave drying ceramic isolators, plaster board and paper web
    Objective:
    To develop appropriate technology based on application of microwaves in manufacturing processes.
  • Industrial and Domestic Hot Water system
    Objective:
    To develop an alternative microwave hot water system to help in the process of reducing operating cost, saving energy and providing a better environment. The system is capable of producing hot water instantaneously and at a preselected temperature up to boiling point.
  • Microwave Heating and Processing Dielectric Fluids
    Objective:
    To investigate the thermal runaway phenomena of grease constituents in isolation and in combination and subsequently develop appropriate applicators for batch production operations.
  • Diamond coating using Microwave Vacuum Deposition Techniques.
    Objective:
    To assess the deposition of diamond coatings on metallic tool surfaces.
  • Investigation of the application of Microwave Technology to Malting
    Objective:
    To develop a microwave technology for heating water in boiler circuit, steep water heating, drying the green malt in the conveying system, alternative technology to conventional kilning.
  • Rapid Curing of Adhesive Bonds in low Dielectric Polymer Sheets using Microwaves
    Objective:
    To assess the potential of using microwave coupling agents and adhesives for heterogeneous sound bonding of low dielectric polymers.
  • Development of a Passive Microwave Radiometer for non-contact medical and industrial thermography applications and Microwave Medical Radiometry for Breast Cancer Detection
    Objective:
    To design and develop a Microwave Radiometer System to measure non-invasively the electromagnetic radiation or emission from an object.
  • Development of a Microwave Hyperthermia Apparatus for Skin Cancer Treatment.
    Objective:
    To desing a newer form of treatment that involves the use of heating effects of applied microwave energy, by bringing cancerous cells to a critical temperature, at which they can be destroyed without causing harm to the healthy cells.