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In Vivo Testing of Blood Vessel Made From Bio-Compatible Material

By Professor Yos Morsi

Tuesday, January 1, 2008

Swinburne and Donghua University have been collaborating on the development of a special designed haemodynamically tested (at Swinburne) and Electrospun (Donhua) tissue engineered blood vessel.

In this project, an electro spun nano-fibers tube scaffold has been prepared into tube scaffold with the inner diameter of 3mm and length of 3cm at the Institute of Biological Sciences and Biotechnology in Shanghai (Professor X Mo) The vessel was implanted into a dog (after autologous cell harvest, in-vitro cell culture and expansion cell, seeding) to replace the defected artery. The newly developed synthetic blood vessel was sutured to the defect area. The blood flow and the integrity of vessel were observed to keep patency. The in vivo trial lasted 4 months.