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A breakthrough technique for super-resolution 3D medical imaging of living cells

Wednesday January 15 2014

CMP Researchers report a new medical imaging technique that may lead to early cancer detection.

A breakthrough technique for super-resolution 3D medical imaging of living cells has been developed that potentially could aid in minimally-invasive surgery and the early detection of cancer.

The researchers, Professor Min Gu, Dr Xiangping Li and Dr Hong Kang, applied a technique announced last year, enabling three-dimensional optical beam lithography at nine nanometres, to two-photon fluorescence endo-microscopy.

Two-photon fluorescence endo-microscopy is a powerful technique for non-invasive, high-resolution imaging of biological tissue.

Using this technique, they have for the first time demonstrated that greater image definition can be achieved with a two-photon probe using a special donut-shaped beam generated from a double-clad optical fibre.

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